Metabolic, Physiological and Behavioral Phenotyping Core

The Metabolic, Physiological and Behavioral Phenotyping Core (also referred to as the Animal Phenotyping Core) is directed by Dr. Nathan Qi and performs a variety of in vivo physiological assessments encompassing glucose homeostasis (glucose tolerance, insulin tolerance, hyperinsulinemic-euglycemic, hypo- or hyperglycemic clamps), lipid metabolism (3H-triolein lipid tolerance, 3H-palmitate FA fluxes) energy homeostasis (indirect calorimetry by CLAMS, Promethion systems with ambient temperature or dietary challenge), ultradian hormone secretion (Culex platform for serial biological fluid sampling from free moving, unrestrained mice), behavioral measurements (learning/memory, locomotor activity, anxiety, depression, meal pattern analysis, operant conditioning). 

Key aims of the core:

  • Provide investigators the essential resources for advanced, standardized phenotyping in mouse models of metabolic diseases caused by dietary, genetic, pharmacologic or other perturbations.
  • Aid MMPC investigators in the design, performance and interpretation of phenotyping assays conducted by the Core.

Please find our standard list of prices and services described in the table below. When you are ready to proceed, please follow the steps to submit a Request for Service.

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Listed prices reflect internal UofM investigator rates, external customers are subject to additional fees, please inquire for a quote.

Test Number Test Name
MI 2404
Blood Sampling/Infusion/Injection: Tail Vein Blood Sampling
$3.97 animal/visit
MI 2405
Blood Sampling/Infusion/Injection: Tail Vein Blood Sampling: plasma (heparin)
$4.08 animal/visit
MI 2406
Blood Sampling/Infusion/Injection: Tail Vein Blood Sampling: plasma (EDTA)
$4.22 animal/visit
MI 2407
Blood Sampling/Infusion/Injection: Tail Vein Blood Sampling: for serium
$4.96 animal/visit
MI 2408
Blood Sampling/Infusion/Injection: Retro Orbital Bleeding (under anesthesia)
$5.87 animal/visit
MI 2409
Blood Sampling/Infusion/Injection: Retro Orbital Bleeding (under anesthesia): plasma (heparin)
$5.98 animal/visit
MI 2410
Blood Sampling/Infusion/Injection: Retro Orbital Bleeding (under anesthesia): plasma (EDTA)
$6.20 animal/visit
MI 2411
Blood Sampling/Infusion/Injection: Retro Orbital Bleeding (under anesthesia): for serium
$7.11 animal/visit
MI 2412
Blood Sampling/Infusion/Injection: Tail Vein Injection
$13.53 per mouse/visit
$15.97 per rat/visit
MI 2413
Blood Sampling/Infusion/Injection: IP Injection
$2.91 per mouse/visit
$3.31 per rat/visit
MI 2414
Blood Sampling/Infusion/Injection: Subcutaneous Injection
$2.71 per mouse/visit
$3.11 per rat/visit
MI 2501
Exercise running & In-cage activity: Treadmill training
$35.11 per week
MI 2502
Exercise running & In-cage activity: Test of Running Capacity (time and distance)
$36.57 per animal/visit
MI 2503
Exercise running & In-cage activity: VO2max (sampling @ per sec)
$64.73 per animal/visit
MI 2504
Exercise running & In-cage activity: In-cage Running Wheel Activity @ RT
$2.49 per animal/day
MI 2601
Behavioral Tests: Open Field Test
$34.31 per mouse
$34.31 per rat
MI 2602
Behavioral Tests: Elevated Plus or Circle Maze
$34.31 per mouse
$34.31 per rat
MI 2603
Behavioral Tests: Y-maze
$34.31 per mouse
$34.31 per rat
MI 2604
Behavioral Tests: Morris Water Maze
$124.08 per mouse
$142.97 per rat
MI 2605
Behavioral Tests: Novel Object Recognition
$34.31 per mouse
MI 2606
Behavioral Tests: Forced Swim Test
$34.31 per mouse
MI 2607
Behavioral Tests: Light/Dark Box
$34.31 per mouse
MI 2608
Behavioral Tests: Rotarod Test
$34.31 per mouse
MI 2609
Behavioral Tests: Tail Suspension Test
$34.31 per mouse
MI 2610
Behavioral Tests: Fear Conditioning Box
$45.44 per mouse
$50.19 per rat

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