*** Effective Immediately, the Animal Phenotyping Core, is NOT accepting any new experiments. As directed by the University's Office of Vice President for Research we have begun ramping down noncritical laboratory research activities until further notice. However, our team continues to be available via email and will be working remotely, on data analysis, study consultation and development, and manuscript preparation, etc. ***
Please note: We will continue to schedule future studies based on the improvement of the situation.
The Metabolism, Bariatric Surgery and Behavior Core (also referred to as the Animal Phenotyping Core) is directed by Dr. Malcolm Low and Dr. Nathan Qi and performs a variety of in vivo physiological assessments encompassing glucose homeostasis (glucose tolerance, insulin tolerance, hyperinsulinemic/euglycemic clamps), energy homeostasis (indirect calorimetry by CLAMS, dietary challenge), ultradian hormone secretion (Culex platform for serial biological fluid sampling from unrestrained mice), behavioral measurements (locomotor activity, meal pattern analysis, operant conditioning) and generation of bariatric surgery models.
Key aims of the core:
- Provide investigators the essential resources for advanced, standardized phenotyping in mouse models of metabolic diseases caused by dietary, genetic, pharmacologic or other perturbations.
- Aid MMPC investigators in the design, performance and interpretation of phenotying assays conducted by the Core.