Metabolism, Bariatric Surgery and Behavior Core

***The Phenotyping Core is now accepting experiments. However, some adjustments have been made in order to remain compliant with social distancing guidelines. Some experiments may take longer to complete so please contact core staff as soon as possible to schedule your study.

The Metabolism, Bariatric Surgery and Behavior Core (also referred to as the Animal Phenotyping Core) is directed by Dr. Malcolm Low and Dr. Nathan Qi and performs a variety of in vivo physiological assessments encompassing glucose homeostasis (glucose tolerance, insulin tolerance, hyperinsulinemic/euglycemic clamps), energy homeostasis (indirect calorimetry by CLAMS, dietary challenge), ultradian hormone secretion (Culex platform for serial biological fluid sampling from unrestrained mice), behavioral measurements (locomotor activity, meal pattern analysis, operant conditioning) and generation of bariatric surgery models. 

Key aims of the core:

  • Provide investigators the essential resources for advanced, standardized phenotyping in mouse models of metabolic diseases caused by dietary, genetic, pharmacologic or other perturbations.
  • Aid MMPC investigators in the design, performance and interpretation of phenotying assays conducted by the Core.

Please find our standard list of prices and services described in the table below. When you are ready to proceed, please follow the steps to submit a Request for Service.

Browse or Search for Services

Listed prices reflect internal UofM investigator rates, external customers are subject to additional fees, please inquire for a quote.

Test Number Test Name
MI2001
Catheterization of jugular vein
$77.30/per mouse
MI2002
Catheterization of carotid artery
$100.10 per mouse
MI2003
Catheterization of jugular vein AND carotid artery
$167.90/per mouse
MI2004
Catheterization of portal vein
$140.40/per mouse
MI2005
Catheterization of portal vein AND carotid artery
$165.00/per animal
MI2006
Catheterization of stomach or bladder
$56.40/per mouse
MI2007
Partial pancreatectomy
$50.70/per mouse (60% removal)
$61.60/per mouse (90% removal)
MI2008
Parabiosis (a surgical union of two mice)
$79.20/per procedure
$62.60 to include the reverse surgery
MI2010
Glucose Tolerance Test (OGTT or IPGTT) including insulin
$85.10/per mouse
MI2011
Glucose Tolerance Test (OGTT or IPGTT) w/o insulin
$50.30
MI2012
Intravenous Glucose Tolerance Test (IVGTT) including insulin
$290.70/per mouse
MI2013
Intravenous Glucose Tolerance Test (IVGTT) w/o insulin
$201.50/per mouse
MI2016
Insulin or Pyruvate Tolerance Test
$50.10/per mouse
MI2017
Hyperinsulinemic-euglycemic clamp + 2 tracers (3H-glucose + 14C-2DG)
$479.00/per mouse
630.30/per rat
MI2018
Hyperinsulinemic-euglycemic clamp + 1 tracer (3H-glucose OR 14C-2DG)
$420.80/per mouse
$522.50/per rat
MI2019
Hyperinsulinemic-euglycemic clamp w/o tracers
$392.40/per mouse
$411.10/per rat
MI2020
Hyperinsulinemic-euglycemic clamp using portal vein infusion
Please Inquire
MI2021
Hyperinsulinemic-euglycemic clamp + steady-state plasma NEFA
$34.30/per mouse
MI2022
Hyperinsulinemic-euglycemic clamp + hepatic glycogen synthesis OR hepatic de novo lipogenesis
$54.70/per animal
MI2023
Hyperglycemic Clamp including insulin
$412.40/per mouse
$440.80/per rat
MI2024
Hyperinsulinemic-hypoglycemic clamp
$378.30/per mouse
$424.30/per rat
MI2025
VO2 & VCO2 with spontaneous activity and food intake @ Room temperature (22 °C)
$43.60/per mouse/per day
$50.31/per rat/per day
MI2026
VO2 & VCO2 with spontaneous activity and food intake, Thermoneutrality (30 °C) and/or cold (as low as 4 °C)
$51.60/per mouse
$8.70/per mouse, subcutaneous implantation (3 days minimum)
$16.70/per mouse, IP implantation (3 days minimum)
MI2028
Non-shivering thermogenesis using injection of norepinephrine (including 24hours acclimation at 30°C)
$74.30/per mouse w/out anesthesia
$79.80/per mouse w anesthesia (pentobarbital, IP)
MI2029
Body Composition (Bruker Minispec LF 90II)
$15.60/per mouse

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