The Metabolic, Physiological and Behavioral Phenotyping Core (also referred to as the Animal Phenotyping Core) is directed by Dr. Nathan Qi and performs a variety of in vivo physiological assessments encompassing glucose homeostasis (glucose tolerance, insulin tolerance, hyperinsulinemic-euglycemic, hypo- or hyperglycemic clamps), lipid metabolism (3H-triolein lipid tolerance, 3H-palmitate FA fluxes) energy homeostasis (indirect calorimetry by CLAMS, Promethion systems with ambient temperature or dietary challenge), ultradian hormone secretion (Culex platform for serial biological fluid sampling from free moving, unrestrained mice), behavioral measurements (learning/memory, locomotor activity, anxiety, depression, meal pattern analysis, operant conditioning).
Metabolic, Physiological and Behavioral Phenotyping Core
Nathan Qi, Core Director
734-232-8223
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Listed prices reflect internal UofM investigator rates, external customers are subject to additional fees, please inquire for a quote.
Test Number | Test Name |
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MI2001
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Catheterization of jugular vein
$74.45 per mouse
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MI2002
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Catheterization of carotid artery
$95.29 per mouse
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MI2003
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Catheterization of jugular vein AND carotid artery
$159.09 per mouse
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MI2004
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Catheterization of portal vein
$124.26 per mouse
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MI2005
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Catheterization of portal vein AND carotid artery
$189.45 per mouse
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MI2006
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Catheterization of stomach, bladder, intestine
$54.00 per mouse
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MI2007
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Partial pancreatectomy
$40.06 per mouse (60% removal)
$49.05 per mouse (90% removal)
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MI2008
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Parabiosis (a surgical union of two mice)
$131.10 per procedure
$96.56 per procedure (reverse surgery)
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MI2009
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Intracranial cannulation
$131.10 per mouse
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MI2010
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Renal capsule implantation
$51.36 per mouse
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MI2011
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Temperature chip or osmotic pump implantation
$12.25 per mouse
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MI2012
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Glucose Tolerance Test (OGTT or IPGTT)
$85.24 per mouse (including insulin measurement)
$47.82 per mouse (without insulin)
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MI2013
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Intravenous Glucose Tolerance Test (IVGTT)
$246.07 per mouse (including insulin measurement)
$183.05 per mouse (without insulin)
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MI2014
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Insulin Tolerance Test (ITT)
$41.98 per mouse
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MI2015
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Hyperinsulinemic-euglycemic clamp + 2 tracers (3H-glucose + 14C-2DG)
$481.90 per mouse
$650.72 per rat
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MI2016
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Hyperinsulinemic-euglycemic clamp + 1 tracer (3H-glucose OR 14C-2DG)
$424.16 per mouse
$548.45 per rat
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MI2017
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Hyperinsulinemic-euglycemic clamp w/o tracers
$388.73 per mouse
$440.79 per rat
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MI2018
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Hyperinsulinemic-euglycemic clamp using portal vein infusion
Please Inquire
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MI2019
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Plasma NEFA during clamp steady-state
$39.43 per mouse
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MI2020
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Hepatic de novo lipogenesis OR hepatic glycogen synthesis
$39.43 per animal
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MI2021
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Hyperglycemic Clamp
$388.73 per mouse
$440.79 per rat
Excluding plasma insulin ($12/sample)
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MI2022
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Hyperinsulinemic-hypoglycemic clamp
$388.73 per mouse
$440.79 per rat
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MI2023
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Whole body energy expenditure (including 1 free body composition)
$41.69 per animal/day (CLAMS)
$44.03 per mouse/day (Premetheon)
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MI2024
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Per temperature setting (thermoneutrality or cold) and temperature scan
$2.42 per mouse
$2.05 per scan (body temperature scan)
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MI2025
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Non-shivering thermogenesis using norepinephrine (including 24h acclimation at 30°C)
$52.30 per mouse (no anesthesia)
$64.63 per mouse (with pentobarbital, IP)
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