Metabolic, Physiological and Behavioral Phenotyping Core

The Metabolic, Physiological and Behavioral Phenotyping Core (also referred to as the Animal Phenotyping Core) is directed by Dr. Nathan Qi and performs a variety of in vivo physiological assessments encompassing glucose homeostasis (glucose tolerance, insulin tolerance, hyperinsulinemic-euglycemic, hypo- or hyperglycemic clamps), lipid metabolism (3H-triolein lipid tolerance, 3H-palmitate FA fluxes) energy homeostasis (indirect calorimetry by CLAMS, Promethion systems with ambient temperature or dietary challenge), ultradian hormone secretion (Culex platform for serial biological fluid sampling from free moving, unrestrained mice), behavioral measurements (learning/memory, locomotor activity, anxiety, depression, meal pattern analysis, operant conditioning). 

Key aims of the core:

  • Provide investigators the essential resources for advanced, standardized phenotyping in mouse models of metabolic diseases caused by dietary, genetic, pharmacologic or other perturbations.
  • Aid MMPC investigators in the design, performance and interpretation of phenotyping assays conducted by the Core.

Please find our standard list of prices and services described in the table below. When you are ready to proceed, please follow the steps to submit a Request for Service.

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Listed prices reflect internal UofM investigator rates, external customers are subject to additional fees, please inquire for a quote.

Test Number Test Name
MI2051
Rectal Temperature Recording (YSI 4600 precision thermometer)
$3.71 per mouse/visit
$4.23 per rat/visit
MI2052
24-hour Urine and/or Fecal Collection
$7.81 per mouse/day (metabolic cage)
$7.02 per mouse/visit (manual fecal collection in home cage)
MI2053
Tissue Dissection/Collection (isoflurane and liquid N2)
$15.56 per mouse (setup fee)
$28.00 per rat (setup fee)
$3.67 per mouse tissue (excluding brain)
$4.27 per rat tissue (excluding brain)
$5.48 per mouse brain
$6.46 per rat brain
MI2054
Tail Vein Blood Sampling (plasma or serum)
$3.71 per animal/visit
$3.87 per animal/visit, for plasma (heparin)
$4.08 per animal/visit, for plasma (EDTA)
$4.74 per animal/visit, for serum
MI2055
Retro-orbital bleeding (under isoflurane anesthesia)
$5.13 per animal/visit
$5.29 per animal/visit, for plasma (heparin)
$5.61 per animal/visit, for plasma (EDTA)
$6.26 per animal/visit, for serum
MI2056
Tail Vein Injection (success rate > 95% in C57BL6 mice)
$12.02 per mouse/visit
$13.27 per rat/visit
MI2057
IP or Subcutaneous Injection
$2.77 per mouse/visit
$3.28 per rat/visit
MI2058
Plasma Glucose (using a colorimetric kit)
$3.60 per sample
MI2059
Plasma insulin (using a ELISA kit)
$15.00 per sample
MI2060
Plasma NEFA (using a colorimetric kit)
$6.93 per sample
MI2061
Plasma Triglyceride (using a colorimetric kit)
$6.35 per sample
MI2063
Tissue glucose TG content
$40.40/per sample
MI2064
Laboratory Assistance or Training
$116.8 per hour
MI2065
Surgical Training (excluding material)
$161.46 per hour
$1,027.50 per day
MI2066
Technician Time
$116.89 per hour
MI2069
Animal Housing (same as ULAM per diem)
Mice-Ventilated: $0.93 per cage/day
Mice-Stationary: $1.05 per cage/day
Mice-Breeding Vented: $1.81 per cage/day
Mice-Nude: $1.35 per cage/day
Rat-Ventilated: $1.64 per cage/day
Rat-Stationary: $1.86 per cage/day
Rat-Breeding Vented: $2.58 per cage/day
Rat-Nude: $3.61 per cage/day
MI2072
Tissue glycogen content
$40.40/per sample
MI2500
Learning and Memory - Spatial Object Recognition
$95.00
MI2501
Learning and Memory - Novel Object Recognition
$95.00/per hour
MI2502
Learning and Memory - Morris Water Maze
$95.00/per hour
MI2503
Motor Activity - Home Cage (Ethovision or Photobeam)
Please Inquire
MI2504
Motor Activity - Open Field Test (Ethovision or Photobeam)
$95.00/per hour
MI2505
Anxiety - Open Field Test (Ethovision or Photobeam)
$95.00/per hour
MI2506
Anxiety - Elevated Plus Maze (Ethovision)
$95.00/per hour
MI2507
Anxiety - Novelty Supressed Feeding Test
$95.00/per hour

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