The Metabolic, Physiological and Behavioral Phenotyping Core (also referred to as the Animal Phenotyping Core) is directed by Dr. Nathan Qi and performs a variety of in vivo physiological assessments encompassing glucose homeostasis (glucose tolerance, insulin tolerance, hyperinsulinemic-euglycemic, hypo- or hyperglycemic clamps), lipid metabolism (3H-triolein lipid tolerance, 3H-palmitate FA fluxes) energy homeostasis (indirect calorimetry by CLAMS, Promethion systems with ambient temperature or dietary challenge), ultradian hormone secretion (Culex platform for serial biological fluid sampling from free moving, unrestrained mice), behavioral measurements (learning/memory, locomotor activity, anxiety, depression, meal pattern analysis, operant conditioning).
Key aims of the core:
- Provide investigators the essential resources for advanced, standardized phenotyping in mouse models of metabolic diseases caused by dietary, genetic, pharmacologic or other perturbations.
- Aid MMPC investigators in the design, performance and interpretation of phenotyping assays conducted by the Core.
Please find our standard list of prices and services described in the table below. When you are ready to proceed, please follow the steps to submit a Request for Service.