Metabolism, Bariatric Surgery and Behavior Core

The Metabolism, Bariatric Surgery and Behavior Core (also referred to as the Animal Phenotyping Core), directed by Dr. Malcolm LowDr. Nathan Qi and Dr. Randy Seeley performs a variety of in vivo physiological assessments encompassing glucose homeostasis (glucose tolerance, insulin tolerance, hyperinsulinemic/euglycemic clamps), energy homeostasis (indirect calorimetry by CLAMS, dietary challenge), ultradian hormone secretion (Culex platform for serial biological fluid sampling from unrestrained mice), behavioral measurements (locomotor activity, meal pattern analysis, operant conditioning) and generation of bariatric surgery models. 

Key aims of the core:

  • Provide investigators the essential resources for advanced, standardized phenotyping in mouse models of metabolic diseases caused by dietary, genetic, pharmacologic or other perturbations.
  • Aid MMPC investigators in the design, performance and interpretation of phenotying assays conducted by the Core.

Please find our standard list of prices and services described in the table below. When you are ready to proceed, please follow the steps to submit a Request for Service.

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Listed prices reflect internal UofM investigator rates, external customers are subject to additional fees, please inquire for a quote.

Test Number Test Name
MI2001
Catheterization of jugular vein
$70.00/per mouse
MI2002
Catheterization of carotid artery
$90.00 per mouse
MI2003
Catheterization of jugular vein AND carotid artery
$150.00/per mouse
MI2004
Catheterization of portal vein
$125.00/per mouse
MI2005
Catheterization of portal vein AND carotid artery
$165.00/per animal
MI2006
Catheterization of stomach or bladder
$50.00/per mouse
MI2007
Partial pancreatectomy
$45.00/per mouse (60% removal)
$55.00/per mouse (90% removal)
MI2008
Parabiosis (a surgical union of two mice)
$70.00/per procedure
$55.00 to include the reverse surgery
MI2009
Radio-telemetry implantation in the aorta or carotid artery
$140.00/per mouse
MI2010
Glucose Tolerance Test (OGTT or IPGTT) including insulin
$80.00/per mouse
MI2011
Glucose Tolerance Test (OGTT or IPGTT) w/o insulin
$45.00
MI2012
Intravenous Glucose Tolerance Test (IVGTT) including insulin
$260.00/per mouse
MI2013
Intravenous Glucose Tolerance Test (IVGTT) w/o insulin
$180.00/per mouse
MI2015
Intravenous Glucose Tolerance Test using portal vein delivery
$35+/per mouse
MI2016
Insulin or Pyruvate Tolerance Test
$45.00/per mouse
MI2016
Insulin or Pyruvate Tolerance Test
$45.00/animal/procedure
MI2017
Hyperinsulinemic-euglycemic clamp + 2 tracers (3H-glucose + 14C-2DG)
$425.00/per mouse
MI2018
Hyperinsulinemic-euglycemic clamp + 1 tracer (3H-glucose OR 14C-2DG)
$350.00/per mouse
MI2019
Hyperinsulinemic-euglycemic clamp w/o tracers
$335.00/per mouse
MI2020
Hyperinsulinemic-euglycemic clamp using portal vein infusion
Please Inquire
MI2021
Hyperinsulinemic-euglycemic clamp + steady-state plasma NEFA
$30.30/per mouse
MI2022
Hyperinsulinemic-euglycemic clamp + hepatic glycogen synthesis OR hepatic de novo lipogenesis
$50.00
MI2023
Hyperglycemic Clamp including insulin
$365.00
MI2024
Hyperinsulinemic-hypoglycemic clamp
$335.00
MI2025
VO2 & VCO2 with spontaneous activity and food intake @ Room temperature (22 °C)
$38.50

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